Week Ending November 7, 2022

Fatty Liver Disease Has Increased Over the Past Two Decades
“Across the world, non-alcoholic fatty liver disease (NAFLD) is increasingly common, according to study results published in The Lancet Gastroenterology & Hepatology.”

Treating liver cancer
“More than 41,000 new cases of primary liver cancer and intrahepatic bile duct cancer will be diagnosed in the U.S. this year, and more than 30,000 people will die of these diseases, according to the American Cancer Society.”

Effectiveness and Safety of Sofosbuvir-Velpatasvir in Patients with Cirrhosis Associated with Genotype 3 Hepatitis C Infection in Xinjiang, China
“Patients with cirrhosis from genotype 3 (GT3) hepatitis C virus (HCV) infection are difficult to cure. This study investigated the effectiveness and safety of sofosbuvir-velpatasvir (SOF/VEL) with and without ribavirin (RBV) in patients with GT3 HCV-infection-related cirrhosis from Xinjiang, China.”

Hepatitis C Can Be Cured in Young People Who Inject Drugs
“Previously thought to be difficult or impossible, one study found HCV and drug use can be treated concurrently in young adults.”

Previously unknown hepatitis B virus pathway from the cell identified
“Around 1.5 million people worldwide become infected with the hepatitis B virus (HBV) every year. A research team led by the Paul-Ehrlich-Institut has identified a previously unknown pathway for the egress of hepatitis B virus particles from cells: researchers were able to visualize intact virus particles in extracellular vesicles (exosomes) for the first time.”

Cirrhosis of the Liver: A Case Report and Literature Review of a Rare Case Presentation of Autoimmune Hepatitis With Systemic Sclerosis
“Systemic sclerosis (SSc) is a chronic systemic disease that affects the skin, heart, lungs, kidneys, gastrointestinal tract, and musculoskeletal system. Although gastrointestinal involvement has been reported in approximately 90% of scleroderma patients, liver involvement is uncommon.”