Week Ending June 21, 2022

How a Nasal Swab Test Can Detect the Risk of Lung Cancer
“There are roughly 225,000 new cases of lung cancer every year in the United States. Early diagnosis and treatment play a large role in improving outcomes. A recently developed nasal swab test could help identify the risk of lung cancer so people can proceed with diagnosis and treatment more quickly.”

Prolonged, low-level radon exposure still a leading cause of lung cancer
“A study shows a strong relationship between prolonged exposure to low levels of radon and lung cancer, indicating a need for enhanced protection measures. Radon gas in the air decays into tiny radioactive particles which can damage lung cells and lead to cancer.”

The reversible fourth-generation EGFR tyrosine kinase inhibitor OBX02-011 overcomes C797S-mediated resistance in lung cancer 
“Osimertinib is an irreversible third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) that was initially developed to overcome the EGFR T790M mutation and is used as a standard therapy in patients with advanced non-small cell lung cancer (NSCLC) with EGFR-activating mutations.”

The Link Between Smoking and Non-Small Cell Lung Cancer
“Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, accounting for about 85 percent of all cases. Smoking is by far its leading cause. Roughly 90 percent of all lung cancer cases are due to tobacco use, including cigarettes, cigars, and pipes.”

Lung cancer: Drug combo improves survival rate without chemotherapy
“Advanced non-small cell lung cancer (NSCLC) accounts for 84% of all lung cancer cases. The American Cancer Society estimated that in 2022, there will be around 236,740 new cases of lung cancer and around 130,180 deaths from the condition in the United States alone.”

Increased Stage I Lung Cancer Diagnoses Driven by NSCLC
“There was a significant increase in the percentage of stage I lung cancer diagnoses between 2010 and 2017, the majority of which were non-small cell lung cancer (NSCLC), according to an analysis of data from the National Cancer Database presented at the 2022 ASCO Annual Meeting.”

Can CT Scans Accurately Detect Lung Cancer?
“Lung cancer is the No. 1 cause of cancer-related death in the United States. Screening with low dose computed tomography (called low dose CT or LDCT) can save lives for people at high risk for this disease.”

Navigating to Earlier Detection of Lung Cancer
“Building on the success of our Lung Cancer Screening program, the McLeod Health team has been detecting lung cancer earlier and saving lives through low-dose CT scans for more than seven years. Since that time the cancer team has expanded the program to include four dedicated nurse navigators, a lung nodule clinic and patient conferences with multiple specialists.”

Roundtable Discussion: Dowlati Breaks Down Updated Treatment Data in SCLC
“During a Targeted Oncology case-based roundtable event, Afshin Dowlati, MD, discussed with participants the results of the CASPIAN and IMpower 133 trials of new regimens for extensive-stage small cell lung cancer.”