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DOH Report Finds Earlier Death Associated with Hepatitis C
“HONOLULU – As part of Liver Cancer Awareness Month in October, the Hawai‘i Department of Health (DOH) has released a report that found hepatitis C was associated with death at an earlier age in Hawaiʻi. “Premature Deaths and Disparities Associated with Hepatitis C: The Hawaiʻi Hepatitis C Mortality Report,” analyzed mortality data from 2000 to 2021 to understand the burden of hepatitis C infections on local communities. The findings will guide efforts to improve liver health and reduce preventable deaths.

This novel report was the first comprehensive analysis of hepatitis C death data for Hawaiʻi. The most important findings from the report include: People with hepatitis C die at a younger age than the general population. Most (88 percent) Hawaiʻi residents with hepatitis C-related deaths did not reach age 75, which was lower than the U.S. life expectancy in 2021. Many deaths occur before retirement age. Among Hawaiʻi residents with hepatitis C-associated deaths, more than 40 percent died before the average retirement age of 65 years (as compared to 23 percent for all causes of death). Progress is being made. Hepatitis C death rates were lower than the national average from 2017 to 2020, with 2.63 deaths per 100,000 in Hawaiʻi compared to 3.45 per 100,000 in the U.S. in 2020. However, disparities in death rates were observed for male and white residents in Hawaiʻi.

Revealing disparities in hepatitis C care for reproductive-aged women to break cycle of viral transmission
“Most pediatric cases of hepatitis C virus (HCV) infection are perinatal, meaning the virus is transmitted from birthing parent to child during pregnancy or birth, according to the Centers for Disease Control and Prevention. If left untreated, hepatitis C infection can lead to worse outcomes later in life, such as chronic liver disease, liver failure, and liver cancer. Identifying disparities in testing and treating hepatitis C among people of reproductive age with opioid use disorder can improve health outcomes for all birthing parents and children.”

Feasibility and Performance of a Point-of-Care Hepatitis C RNA Assay in a Community Supervision Cohort
“Progress toward hepatitis C virus (HCV) elimination in the US has been stalled by reliance on a multistep diagnostic algorithm to confirm viremia, reducing access to curative treatment.”

New Research Supports Universal HCV Screening Over Risk-Based Testing
“The study found 1.4 million people aged 12-59 with current HCV infection, including over 500,000 without injection drug use history.”

State Spotlight Series: Syndemic Approaches to Substance Use and Infectious Disease
“Governors and their teams are responding to a rapid rise in syphilis and congenital syphilis cases. The National Governors Association Center for Best Practices (NGA Center) is working to support states and territories in implementing a “syndemic” approach to this and other infectious diseases, recognizing that these outbreaks are intertwined with substance use. A syndemic refers to intersecting epidemics that are not only concurrent or sequential, but also have synergistic relationship, with overlapping or interactive risk factors, and often a context of shared social and behavioral risk factors and healthcare access gaps.”