Weekly News

Weekly news updates are currently posted on our homepages, weekly news pages and sent directly to your inbox to provide up-to-date information on what has been covered in the news regarding lung cancer, hepatitis C and complementary health & wellness in the previous week.

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My Choices News

Week Ending June 14, 2021

This Quick Migraine Massage Can Actually Help With Your Pain
“If you’ve ever had a migraine (or just a regular headache, TBH), you know they’re the absolute pits. Yes, the pits! They’re 1) painful, 2) a nuisance to functioning as a human, 3) miserable, and, oh yeah, 4) painful!”

5 Fenugreek Health Benefits You Should Know, According to a Nutritionist
“Interest in natural remedies has skyrocketed, with more people turning to food as medicine. That means functional foods-foods that have a positive impact on health beyond the nutrients they provide-are in demand.”

Can Vitamins and Supplements Help You Sleep?
“You know the feeling: You toss and turn, night after night and nothing seems to quite do the trick. You’ve tried over-the-counter sleep aids and even some supplements, but you’re beginning to wonder if there’s a more natural way to get some extra zzz’s.”

Poor oral health linked to muscle loss and diabetes
“The strict measures implemented to prevent the spread of infection have severely reduced access to dental services. This situation led to a rapidly growing backlog of patients in need of oral treatment and care.”

How To Support Your Immune System On A Daily Basis, So It’s Ready For Anything
“Many of us tend to only consider our immunity when there’s an immediate threat: a cold going around the office, a seasonal flu, air travel, the list goes on. However, the reality is, keeping your immune system strong should take precedence at all times.”

Plant-derived compound may help treat chronic pain
“The opioid system in the human body comprises many proteins, receptors, and other compounds that all play a vital role in controlling people’s pain responses and behaviors toward reward and addiction.”

Overcoming midlife barriers to exercise and better health
“Just 30 minutes of movement—anything that gets your heart beating faster—five times a week is all it takes to meet federal guidelines for physical activity. In fact, the goal is 150 minutes a week, whether it’s split up daily or not.”

Why is gardening so good for your mental and physical health?
“With a growing body of research backing the idea that gardening can have measurable benefits to both mental and physical health, barely a week goes by in the horticultural press without a story on the positive impact it can have. As a geeky scientist, however, I wanted to know what it is specifically about growing plants that has this effect – and if we can answer this question could we make gardening an even more effective therapeutic exercise?”

Hepatitis C News

Week Ending June 14, 2021

FDA Approves Two Hepatitis C Treatments for Younger Children
“On June 10, the Food and Drug Administration (FDA) extended its approval of Epclusa (sofosbuvir/velpatasvir) and Mavyret (glecaprevir/pibrentasvir) for the treatment of hepatitis C in children ages 3 and older. Both combination pills are effective against all genotypes of hepatitis C virus (HCV).”

Synthetic overhaul for hepatitis C drug could ease manufacturing demands
“A team at Merck & Co has developed a five-step method for synthesising uprifosbuvir with a 50-fold increase in yield over the previous manufacturing process. The scalable strategy minimises undesirable side products and could be adapted to synthesise a range of nucleosides to help meet global demand for antiviral therapies.”

One Simple Test Prevents This Deadly Cancer
“It’s one of the deadliest cancers and yet, you might not even realize you have it or that you’re at risk… The American Cancer Society estimates that this year, we’ll see more than 42,000 new cases of liver cancer. And about 30,000 folks will die from this extremely deadly form of cancer.”

What to know about hepatitis C and psoriasis
“Psoriasis is an inflammatory condition that causes itchy patches to form on the skin. Hepatitis C is a liver disease that occurs due to the hepatitis C virus. Research is still ongoing, but evidence suggests the two conditions may interact and exacerbate each other’s symptoms.”

Lung Cancer News

Week Ending June 14, 2021

ASCO 2021 recap: Lynparza’s lift, Grail goes on, LAG validation & more
“The American Society of Clinical Oncology’ annual meeting featured news highlights from the Merck, Novartis, and other drug giants. Meanwhile, some small biotechs rode the coattails of their larger counterparts and others forged their own paths with promising early results for new cancer drug targets.”

How Do Immunotherapy Treatments Work for Small Cell Lung Cancer?
“Small cell lung cancer (SCLC) is a less common but aggressive type of lung cancer. Symptoms of SCLC often don’t show up until later stages of cancer, when it has spread to other areas of the body.”

Radiologists and others launching large-scale initiative to tackle incidental lung nodule blind spot
“Radiologists, pulmonologists and other lung care stakeholders are launching a nationwide initiative to tackle ongoing challenges addressing incidental pulmonary nodules that may turn out to be cancerous.”

Opdivo-Yervoy Combination Could Benefit Patients with Non-Small Cell Lung Cancer
“After a four year follow up, a combination of Opdivo (nivolumab) and Yervoy (ipilimumab) continued to prolong survival in patients with advanced non-small cell lung cancer, according to findings presented at the virtual 2021 ASCO Annual Meeting.”

Amgen Lung Cancer Drug Approved by FDA
“The U.S. Food and Drug Administration gave accelerated approval to Lumakras, a drug from Amgen Inc. for adult patients with non-small cell lung cancer.”

Study Explores Potential of Liquid Biopsy in Early-Stage NSCLC
“The study explores data on liquid biopsy approaches outside of circulating tumor DNA—a commonly used approach for liquid biopsy—and includes novel methods like non-coding RNA.”

Cedars-Sinai Cancer names thoracic medical oncology director
“Sukhmani K. Padda, MD, has been selected to direct thoracic medical oncology at Cedars-Sinai Cancer. Padda’s research focuses on therapies for thoracic cancers. She has a particular interest in improving treatment for patients with rare thoracic tumors — such as thymic malignancies and lung neuroendocrine tumors — and genomic subsets of lung cancer, such as KRAS- and EGFR-positive tumors. Padda also conducts research into tumor biomarkers to help ensure optimal treatment.”

VIDEO:
Rationale for the GEMSTONE-302 Study in Lung Cancer
“Jamie E. Chaft, MD, discusses the background behind the phase 3 GEMSTONE-302 trial of platinum-based chemotherapy with placebo or CS1001 as front-line treatment for patients with advanced non-small cell lung cancer.”

Lung Cancer News

Week Ending June 8, 2021

Data reflect disparities in use of next-generation sequencing for lung cancer
“Only one in four Black patients with advanced or metastatic non-small cell lung cancer underwent next-generation sequencing before first-line therapy compared with one in three white patients, according to results of a retrospective study.”

ASCO 2021: Lumakras, First Approved KRAS-targeting Cancer Drug, Looks Promising
“On the heels of last week’s accelerated approval of Lumakras (sotorasib) by the FDA, researchers presented results today from the phase 2 trial that led to drug’s approval at the annual meeting of the American Society of Clinical Oncology.”

New targeted therapy provides survival benefit in KRAS G12C-mutated lung cancer
“Results from the Phase II cohort of the CodeBreaK 100 study showed that treatment with the KRAS G12C inhibitor sotorasib achieved a 37.1% objective response rate and 12.5 months median overall survival in previously treated patients with KRAS G12C-mutated non-small cell lung cancer (NSCLC), according to researchers from The University of Texas MD Anderson Cancer Center. The findings were presented today at the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting and published in the New England Journal of Medicine.”

ARROW Trial Update Continues to Support Pralsetinib Use, Biomarker Testing in RET Fusion+ NSCLC
“Durable responses coupled with a tolerable safety profile of pralsetinib (Gavreto) in patients with RET fusion–positive non–small cell lung cancer (NSCLC) was reported from the ARROW trial (NCT03037385) at the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting, further supporting use of the agent in this patient subset.1”

Better Responses Observed With Selpercatinib Versus Prior Systemic Therapies for RET+ NSCLC
“According to data from the pivotal phase 1/2 LIBRETTO-001 trial (NCT03157128) of selpercatinib (Retevmo) in patients with RET fusion–positive non–small cell lung cancer (NSCLC), the kinase inhibitor was able to induce consistent antitumor benefit regardless of treatment in prior lines of therapy.1”

Nucleix, MD Anderson Partner on Methylation-Based Lung Cancer Dx Tests
“NEW YORK – Israeli molecular diagnostics firm Nucleix said on Thursday that it has signed a research and license agreement with the University of Texas MD Anderson Cancer Center to evaluate and develop methylation assays focusing on lung cancer.”

Lung Cancer Research Foundation and EGFR Resisters Announce Partnership
“Groups join forces to fund mutation-specific research
NEW YORK, June 3, 2021 /PRNewswire/ — The Lung Cancer Research Foundation (LCRF) is excited to announce a partnership with leading lung cancer patient advocacy group, the EGFR Resisters. This multi-year partnership will kick off on June 6th, National Cancer Survivor’s Day, in a joint effort in 2021 to fund an LCRF Pilot Grant related to EGFR positive lung cancer.”

Atezolizumab Extends Disease-Free Survival in Patients with PD-L1 Positive Early NSCLC
“Pharmaceutical maker Roche says its monoclonal antibody (atezolizumab) Tencentriq has been shown to be successful at reducing the risk of recurrence or death in a subset of patients with non-small-cell lung cancer (NSCLC) whose tumors express at least 1% programmed death-ligand 1 (PD-L1).”

Hepatitis C News

Week Ending June 8, 2021

Experts encourage screenings as hepatitis cases on the rise
“New data from the CDC reports that there was also a discrepancy between the number of reported infections and the projected true number of cases.”

For Patients with Hepatitis C, a Model of Community Care
“Karen King found out that she’d contracted hepatitis C about a year after a boyfriend died of a fentanyl overdose. A shared needle was the cause, she said, although she had tried to sterilize it.”

Hepatitis C Micro-Elimination beyond Prison Walls: Navigator-Assisted Test-and-Treat Strategy for Subjects Serving Non-Custodial Sentences
“BACKGROUND AND AIMS: The Spanish prison population includes two groups: people in prison and those who are serving non-custodial sentences. The latter has not yet been studied. This study aims to describe this population and the results of a test-and-treat strategy for hepatitis C including a holistic health assessment.”

Fast Five Quiz: Are You Prepared to Confront Hepatitis C?
“Hepatitis C is a liver disease caused by the hepatitis C virus (HCV). It is a major public health problem. Infection with HCV can lead to both acute and chronic hepatitis, varying in severity from a mild illness of short duration to a serious, lifelong disease. Exposure to infected blood is the principal mode of HCV transmission.”

Pharmacist-led HCV Treatment Programs Helps Patients Follow Through
“A pharmacist-led program for hepatitis C virus (HCV) treatment could enable patients to achieve a sustained virologic response while adhering to the desired treatment regimen.”

Hepatitis C Virus Persistence after Spontaneous or Treatment-Induced Resolution of Hepatitis C
“It is presumed that resolution of hepatitis C, as evidenced by normalization of liver function tests and disappearance of hepatitis C virus (HCV) RNA from serum, as determined by conventional laboratory assays, reflects virus eradication.”

The road to a hepatitis-free future
“A new California bill is taking action to bridge disparities in testing and treatment for the liver diseases hepatitis B and C.”

My Choices News

Week Ending June 8, 2021

Can Essential Oils Help with Crohn’s Disease?
“Crohn’s Disease is a type of inflammatory bowel disease (IBD) that affects over half a million people in the United States. People with Crohn’s disease often have periods of remission and then relapses of symptoms.”

ASCO: Oncologists Underestimate Patient Use of Complementary Medicine
“Oncologists may substantially underestimate how many breast cancer patients are using complementary medicine, according to the results of a survey scheduled to be presented at the annual meeting of the American Society of Clinical Oncology, held virtually from June 4 to 8.”

Nutrition Break: Celebrate June as Men’s Health Month
“June is National Men’s Health Month which focuses on increasing awareness of men’s health problems and encourages early detection and treatment of disease.”

What Is Eccentric Exercise—And Why Should You Incorporate It Into Your Training Program?
“Going through the motions is never a good idea when it comes to fitness. Ask any trainer, and they’ll tell you it’s about quality, not quantity—and that phoning it in is more likely to hurt than help you.”

The Future Of Integrative Health And Medicine
“Mimi Guarneri, MD, FACC, ABOIM, is a board-certified cardiologist, Medical Director and Founder of Guarneri Integrative Health Inc. at Pacific Pearl La Jolla, Founder and former Medical Director of Scripps Center for Integrative Health in La Jolla California, and Founding President of the Academy of Integrative Health and Medicine. Here are insights about her important mission and including her work with Deepak Chopra.”

Integrative Medicine for Brain Health: Why Neurologists Should Care
“The field of integrative medicine is gaining a steadily growing interest base among patients and healthcare professionals alike. Defined as healing-oriented practice with a focus on lifestyle interventions, offering patient-centered care addressing physical, mental, and spiritual well-being, it can fill the gaps that many perceive in our traditional healthcare environment.”

6 Surprising Health Benefits of Pomegranates
“Pomegranates may be tricky to break into, but it’s definitely worth the effort, especially if heart disease runs in your family. Pomegranate health benefits stem from its rich supply of vitamins, minerals and antioxidants your body needs every day to keep your cardiovascular system running smoothly and prevent diseases like cancer. Half a pomegranate counts as one serving of fruit, so enjoy this bright, tart and healthy food with gusto.”

Elimination diet: Purpose, method, and more
“An elimination diet can help a person identify foods that cause discomfort or symptoms of an allergic reaction.”

Mental health and exercise
“Four-time Grand Slam champion Naomi Osaka is one of the fittest and highest-earning women in the world. She is best known for her exploits on the tennis court and several endorsements in her native Japan and the USA. However, she has been grabbing headlines over her struggles off the court.”

The 7 Most-Important Nutrients for Healthy Skin
“As you’ve likely figured out by now, what you eat is a vital part of keeping your skin radiant for the long-haul. Sure, retinols and jade rollers provide their own benefits when it comes to the vitality of your dermis. But they can’t undo a diet that’s lacking in key nutrients for healthy skin.”

Moderately high blood pressure: Exercise should be first-line treatment
“The advice from the AHA for otherwise healthy adults with moderately elevated blood pressure and blood cholesterol is to “sit less and move more.” Together with the ACC, the AHA has released a new scientific statement that stresses the value of recommending physical exercise as the first line of treatment for such individuals.”

Try These Ab Workouts to Strengthen Your Core
“Whether you’re trying to build a six-pack or just trying to tone your body, ab workouts are a terrific way to get in shape and strengthen your core. Plus, ab exercises require no extra equipment and can be done from just about anywhere.”

What’s The Point Of Exercise?
“Exercise is a relatively recent phenomenon. After all, it’s difficult to imagine a caveman on a treadmill. And it’s safe to say that paleolithic humans never pumped iron. But something changed as we moved from the plow to the Peloton. Exercise — physical exertion for the purpose of improving health or fitness — became a huge part of modern life, and a nearly $100 billion global industry.

VIDEO/AUDIO

The Doctor Is In: Integrative Health & Wellness

NUTRITION AND LIFESTYLE CHANGES TO IMPROVE YOUR HEADACHES

Lung Cancer News

Week Ending June 2, 2021

Biodesix, Addario Lung Cancer Institute Enroll First Patient in NSCLC Biomarker Study
“NEW YORK – The Addario Lung Cancer Medical Institute and Biodesix said on Wednesday that they have enrolled the first non-small cell lung cancer patient in a trial evaluating biomarkers predictive of response to immunotherapy using Biodesix’s Primary Immune Response, or PIR, test.”

Key to Leveraging Emerging Approaches in Lung Cancer Lies in Balancing Benefit With Risk
“Novel immunotherapy combinations are gaining ground in the frontline treatment of patients with lung cancer, but the toxicities associated with these regimens must be weighed against the benefit they provide, according to Michael Shafique, MD. Emerging approaches, such as next-generation antibody-drug conjugates (ADCs), could potentially overcome tolerability challenges and provide an option to those who progress on immunotherapies.”

FDA approves Amgen drug for lung cancer with specific mutation
“The medication is designed to target a gene mutation that occurs in about 13 percent of non-small cell lung cancers. The U.S. Food and Drug Administration on Friday approved an Amgen drug for non-small cell lung cancer with a specific mutation in a gene known as KRAS in patients whose disease has worsened after treatment with chemotherapy or other medicines.”

Large-scale Lung Cancer Clinical Study Demonstrates Accuracy and Sensitivity of Fluxion’s ERASE-Seq Liquid Biopsy
“Fluxion Biosciences announced the publication of a paper on ERASE-Seq™ liquid biopsy with molecular amplification pools (MAPs). The paper, “Sensitivity, specificity, and accuracy of a liquid biopsy approach utilizing molecular amplification pools”, published in Nature Scientific Reports on May 24, is co-authored by researchers at Fluxion and the Hospices Civils de Lyon Cancer Institute. Data showed the ERASE-Seq/MAPs approach to have a 98.8% concordance to the benchmark droplet digital PCR (ddPCR) approaches.”

Don’t Delay Lung Cancer Surgery, Study Suggests
“FRIDAY, May 28, 2021 (HealthDay News) — Surgery soon after a diagnosis of early-stage lung cancer is crucial in reducing the risk of recurrence and death, a new study finds.”

Video:
Immunotherapy for First-Line Extensive-Stage SCLC
“A discussion regarding typical response rates to frontline therapy for extensive-stage small cell lung cancer and considerations for incorporating an immunotherapy agent into first-line treatment.”

Dr. Socinski on the Utility of ctDNA Testing in Lung Cancer
“Mark A. Socinski, MD, executive medical director of the AdventHealth Cancer Institute, discusses the utility of circulating tumor DNA (ctDNA) testing in lung cancer.”

Hepatitis C News

Week Ending June 2, 2021

Based on WHO targets, care model improves hepatitis C management in dialysis facilities
“A collaborative approach between nephrologists and gastroenterologists led to improvements in the diagnosis and treatment of hepatitis C virus across 31 dialysis facilities in Changhua County, Taiwan.”

A Pathway to Success on HCV Treatment and Elimination
“Hepatitis C virus (HCV) continues to cause high mortality, with the rate of HCV-related deaths among American Indian and Alaska Native (AI/AN) people more than double the national rate.”

Pregnant People Should Be Screened for Hepatitis C
“Individuals should receive screening for hepatitis C during every pregnancy, according to a practice advisory crafted by the American College of Obstetricians and Gynecologists and endorsed by the Society for Maternal-Fetal Medicine.”

What happens after curing hepatitis C? Avoiding, minimising or accepting the risks of re-infection
“As part of the Swiss HCVree trial, MSM living with HIV and hepatitis C received direct-acting antivirals for hepatitis C. Men reporting sexual risk behaviour also received behavioural counselling aimed at teaching risk reduction strategies.”

How hepatitis C virus evades the immune system
“Researchers from Osaka University discover a novel molecular mechanism by which hepatitis C virus evades the immune system to cause chronic infection”

Access to viral hepatitis diagnosis and treatment is still limited: WHO
“Hepatitis B and C cause 1.1 million deaths and 3 million new infections every year, respectively, according to the World Health Organization (WHO). But diagnosis and treatment remain low.”

Syringe Services Programs Are Vital to Ending the Hepatitis C Epidemic
“In 2015, Scott County, Indiana, found itself in the midst of one of the most severe injection drug use-related HIV outbreaks in United States history. The syringe services program was created after more than 200 people in the county of only 24,000 had been diagnosed with HIV. Since the primary cause of the outbreak was due to the sharing of the contaminated needles, the SSP enabled the residents newly living with HIV to get into care and become virally suppressed.”

My Choices News

Week Ending June 2, 2021

Oncologists underestimate patient use of complementary medicine
“In late 2020, IQVIA conducted a national survey of 115 clinical oncologists who treat breast cancer and 164 breast cancer patients who had been diagnosed within two years of the survey.

Is the microbiome another organ? Maybe we should treat it as such
“In this feature, we hear from two United Kingdom-based researchers whose work focuses on obesity and metabolism: Dr. Petra Hanson and Dr. Thomas M. Barber. They discuss the microbiome, the marketing hype behind probiotics, and the future direction of research.”

How to Overcome Beginner’s Frustration With Meditation
“Have you been meditating lately? If so, you’ve got lots of company, as people the world over have embraced the practice to find calm and comfort during the coronavirus pandemic. But if you’ve tried it and quickly given up, you’ve also got lots of company, meditation experts say.”

Restoring health and fitness with exercise
“If COVID-19 restrictions have kept you home exercising less and eating more, it could be affecting your health as could the stress, boredom and isolation of this time. Exercise can help.”

How Acupuncture Helped My Crohn’s Disease
“Treating Crohn’s disease is a tricky thing since one approach does not fit all. For some people, just taking medications is enough. Others may rely more on holistic or complementary approaches. Personally, I feel my best with a combination of both.”

Medical myths: All about allergies
“For Asthma and Allergy Awareness Month, this edition of the Medical Myths series tackles some of the many myths and misconceptions associated with allergies.”

Should You Take a Food Sensitivity Test? Here’s What Health Experts Have to Say
“You might want to consider a food sensitivity test if you struggle with symptoms like headaches, skin woes, or indigestion. Here’s what to know before ordering one.”

What Is Reiki And How Does It Work?
“Reiki may sound “new age” to some, but it’s anything but new. In fact, it’s a form of energy healing with roots in ancient cultures. Reiki uses what’s known as universal life force energy—ki or qi—to improve people’s lives and ailments.”

Lung Cancer News

Week Ending May 24, 2021

The Chance to Make a Difference Made Herbst a Lung Cancer Pioneer
“Roy S. Herbst, MD, PhD, was inspired to become an oncologist during his first week as an MD/PhD candidate at Cornell University and The Rockefeller University, thanks in part to Ralph L. Nachman, MD, longtime chair of Weill Department of Medicine at Weill Cornell Medical College.”

New Hope For Early Stage Non-Small Cell Lung Cancer Patients: Immunotherapy After Surgery Lowers Risk of Recurrence
“Use of the cancer immunotherapy treatment atezolizumab after surgery and chemotherapy lowers the risk of tumor recurrence in people with early-stage non-small cell lung cancer (NSCLC), according to new research.”

Johnson & Johnson snares FDA nod for first exon 20-targeted drug in EGFR lung cancer
“Just a few short months after Johnson & Johnson’s Janssen unit sent its targeted non-small cell lung cancer (NSCLC) drug amivantamab to the FDA, the regulator has come back with a green light—a very specific one.”

Edwards Comprehensive Cancer Center offers lung cancer screenings
“HUNTINGTON — The Edwards Comprehensive Cancer Center is now offering a lung cancer screening clinic the third Monday of each month from 8 a.m. to noon. Eligible patients can schedule without a physician referral.”

HonorHealth robot helps detect lung cancer
“HonorHealth’s Scottsdale Shea Medical Center is the first hospital in the state to perform a robotic-assisted bronchoscopy using shape-sensing technology.”

U.S. FDA Accepts Regulatory Submission for Sintilimab in Combination with Pemetrexed and Platinum Chemotherapy for the First-Line Treatment of People with Nonsquamous Non-Small Cell Lung Cancer
“SAN FRANCISCO and SUZHOU, China, May 18, 2021 /PRNewswire/ — Innovent Biologics, Inc. (HKEX: 01801) and Eli Lilly and Company (NYSE: LLY) today jointly announced that the U.S. Food and Drug Administration (FDA) accepted for review a Biologics License Application (BLA) for sintilimab injection in combination with pemetrexed and platinum chemotherapy for the first-line treatment of people with nonsquamous non-small cell lung cancer (NSCLC). This is the first U.S. regulatory submission of sintilimab, a PD-1 inhibitor being developed and commercialized under a global collaboration agreement between Innovent and Lilly.”

Video:
Dr. Socinski on the Evolving Paradigm of Targeted Therapy in Lung Cancer
“Mark A. Socinski, MD, executive medical director of the AdventHealth Cancer Institute, discusses the evolving paradigm of targeted therapy in lung cancer.”

Weekly News Update.
Caring Ambassadors Program provides 3 weekly news updates covering Lung Cancer News, Hepatitis C News, and My Choices© Update. Receive them delivered weekly to your inbox.