Why lung cancer belongs in the women’s health conversation
“Cancer mortality in the United States has steadily declined for more than three decades, with millions of lives saved through smoking cessation, earlier detection, and improved treatment. But the epidemiology of lung cancer is shifting in ways we can no longer ignore. Beginning in 2021, lung cancer incidence in women under 65 surpassed that of men for the first time. The progress we are making in this disease is real, but it doesn’t tell the whole story.”
Common p53 genetic mutation reveals Achilles’ heel in lung cancer
“A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the tumor suppressor p53 gene—found very frequently in human tumors—hijack DNA replication in cancer cells. The new findings published in Cell Death & Differentiation support an innovative framework for how targeting this new pathway could help to stop the replication of lung tumor cells and thwart tumor growth.”
FDA Cites Manufacturing Issues in Lung Cancer Drug Rejection
“The U.S. Food and Drug Administration (FDA) declined the approval of retifanlimab-dlwr (Zynyz) for non-small cell lung cancer (NSCLC) over concerns about the PD-1 inhibitor’s manufacturing plant.”
Picture Health publishes study findings for lung cancer AI biomarker
“Researchers found that QVT scores at the start of treatment independently predicted survival outcomes, and that early decreases in QVT scores during treatment appeared sooner than traditional tumor response measures, Picture Health said.”
Managing Myelosuppression in Small Cell Lung Cancer: The Case for Trilaciclib
“Trilaciclib protects bone marrow before SCLC chemotherapy, sharply reducing neutropenia, anemia, and thrombocytopenia, improving fatigue and keeping treatment on schedule without weakening tumor kill.”
A Bad Case of COVID or Flu May Raise Lung Cancer Risk Years Later
“New research from UVA Health’s Beirne B. Carter Center for Immunology Research and the UVA Comprehensive Cancer Center suggests that severe cases of COVID-19 and influenza may create conditions in the lungs that make cancer more likely to develop later. The study also found that vaccination appears to prevent these harmful effects.”
Tobacco tax, pesticide monitoring could help address Iowa’s high cancer rates, researchers say
“These UI researchers and staff presented preliminary information gathered in a yearlong research project conducted through a UI partnership with the Iowa Department of Health and Human Services. Lawmakers had approved $1 million in funding last year for the project, seeking to identify the factors leading to Iowa’s ranking as having the second-highest rate of new cancer cases in the country, and as one of only two states with a rising rate of new cancers in 2025.”
The telltale lung: A new clue for early-stage lung cancer
“Led by oncologist and cancer researcher Dr. Frank Weinberg, the scientists looked at lung cells and fluids from 20 cancer patients. They noticed the patients’ lungs shared a unique combination of molecules. That combination, they realized, is a telltale warning sign that can help them detect, treat and, perhaps, even prevent lung cancer in its earliest stages.”
