Intensive Program Helps People Being Screened for Lung Cancer Quit Smoking
“When people who smoke are screened for lung cancer, studies have suggested that the screening visit can be an opportune time for health care providers to offer them ways to stop smoking. Results from a large clinical trial now show that a comprehensive program that integrates intensive counseling and cessation medications may be a particularly effective way of accomplishing that goal.”
Study reveals gaps in lung cancer screening despite updated guidelines
“Since 2021, when lung cancer screening guidelines began to include younger people and those with a lower smoking history, the number of screenings climbed, but significant gaps remain, especially among people with limited access to healthcare, according to a new study led by researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine.”
Novel selective strategies targeting the BCL-2 family to enhance clinical efficacy in ALK-rearranged non-small cell lung cancer
“ALK (anaplastic lymphoma kinase) rearrangements represent the third most predominant driver oncogene in non-small cell lung cancer (NSCLC). Although ALK inhibitors are the tyrosine kinase inhibitors (TKIs) with the longest survival rates in lung cancer, the complex systemic clinical evaluation and the apoptotic cell death evasion of drug-tolerant persister (DTP) cancer cells may limit their therapeutic response.”
RYBREVANT® (amivantamab-vmjw) plus LAZCLUZE™ (lazertinib) significantly outperforms standard of care in first-line EGFR-mutated lung cancer with compelling new data at ELCC 2025
“Median overall survival improvement projected to exceed one year with much-anticipated overall survival analysis showing statistically superior result versus Osimertinib. Preventative dermatologic regimen meets primary endpoint and enhances patient experience.”
When Lobectomy Is Out: Selecting Treatment for Stage 1 Non-Small Cell Lung Cancer in High-Risk Patients
“The American Association for Thoracic Surgery (AATS) published a consensus statement defining and outlining proper assessment of these high-risk patients in 2021. In late 2024, AATS published a follow-up document: consensus on how to choose more appropriate treatment for high-risk patients. Alternatives to lobectomy include sublobar resection, stereotactic ablative radiotherapy (SABR) and image-guided thermal ablation (IGTA).”
Wildfire Exposure Confers Longer Length of Stay Following NSCLC Surgery
“Patients who received curative-intent surgery for non–small cell lung cancer (NSCLC) at facilities impacted by a wildfire disaster experienced longer length of stay (LOS) vs similar patients who underwent treatment at times when no disasters occurred, according to findings published in the Journal of the National Cancer Institute.”
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Latest Advances in Management of Advanced NSCLC with ALK or ROS1 Mutations
