Risk for lung cancer reoccurrence may be associated with OSA-related hypoxemia
“Key takeaways: In univariate analysis, a 4% oxygen desaturation index greater than 15 was significantly linked to lung cancer reoccurrence. Two hypoxic burden measures continued to be significant in adjusted analysis.”
Study links neighborhood violence, lung cancer progression
“CHAMPAIGN, Ill. — Scientists have identified a potential driver of aggressive lung cancer tumors in patients who live in areas with high levels of violent crime. Their study found that stress responses differ between those living in neighborhoods with higher and lower levels of violent crime, and between cancerous and healthy tissues in the same individuals.”
Lung cancer metabolomics: a pooled analysis in the Cancer Prevention Studies
“This is the largest prospective study examining untargeted metabolic profiles regarding lung cancer risk. Sphingomyelin (d18:0/22:0), a sphingolipid, and taurodeoxycholic acid 3-sulfate, a bile salt, may be risk factors and potential screening biomarkers for lung cancer. Lipid and amino acid metabolism may contribute significantly to lung cancer etiology which varied by smoking status.”
Nurse training key to improving cancer screening for transgender and gender diverse individuals
“The lack of culturally safe health screening for people who are transgender and gender diverse (TGD) is putting them at greater risk of cancer going undetected, but nurse practitioners could be trained to help close the gap.”
Cancer and the Question of Faith
“We recognize that cancer can raise profound spiritual and existential questions. This issue explores the relationship between cancer and faith as we hear from individuals who have found solace in their beliefs during challenging times and speak with experts about the impact that cancer can have on a person’s spiritual views.”
I’m a 34-Year-Old Nonsmoker Who Got Lung Cancer. These Were My First Symptoms
“Ashley Vassallo, 34, is young, active, and a nonsmoker, so when the Bay Area resident had a cough, doctors assumed it was due to COVID or another common ailment. But Vassallo was actually in the early stages of lung cancer, which is often considered one of the most preventable types: Roughly 70% of cases are a direct result of cigarette smoking. However, lung cancer among women under 50 is rising—and that doesn’t seem to correspond with an increase in smokers.”
Drug trial results show lung cancer patients are living longer
“Pfizer has announced promising follow-up results from its Phase 3 CROWN trial evaluating LORBRENA (lorlatinib, a third-generation ALK inhibitor) in 296 people with previously untreated, anaplastic lymphoma kinase (ALK)-positive advanced non-small cell lung cancer (NSCLC).”
Entrectinib in ROS1-positive advanced non-small cell lung cancer: the phase 2/3 BFAST trial
“Although comprehensive biomarker testing is recommended for all patients with advanced/metastatic non-small cell lung cancer (NSCLC) before initiation of first-line treatment, tissue availability can limit testing. Genomic testing in liquid biopsies can be utilized to overcome the inherent limitations of tissue sampling and identify the most appropriate biomarker-informed treatment option for patients.”
