Ensuring Coverage of Faster Biomarker Testing in Lung Cancer: Robert Kratzke, MD
“Delays in molecular testing for patients with non–small cell lung cancer (NSCLC) can lead to treatment lags that cost lives, warned Robert Kratzke, MD, professor of medicine and head of medical oncology at the University of Minnesota.”
Frontline LDRT Plus Atezolizumab Combo Shows Efficacy in ES-SCLC
“The addition of low-dose radiotherapy (LDRT) to frontline atezolizumab (Tecentriq) plus chemotherapy was found to be well tolerated and effective as a treatment for patients with extensive-stage small cell lung cancer (ES-SCLC), according to results from the phase 2 MATCH trial (NCT04622228) published in International Journal of Radiation Oncology, Biology, and Physics.”
TILs: What Are They and How Are They Used in Cancer Treatment?
“Tumor-infiltrating lymphocyte, or TIL, therapy uses a patient’s own immune system T cells to fight cancer. The therapy involves removing T cells from a piece of the patient’s tumor – where the T cells have congregated after being alerted to the cancer – growing them outside the body, then re-infusing them by the billions to attack the disease.”
Microplastics found to trigger cancer-linked changes in lung cells
“Although the respiratory system is one of the main entry points for microplastics and nanoplastics (MNPs) from the air into the body, little is known about the effects of these tiny particles on the lungs. Researchers at MedUni Vienna have now demonstrated for the first time that MNPs can trigger malignant changes in lung cells that are associated with the development of cancer. The findings were published in the Journal of Hazardous Materials and once again underline the urgent need for action to reduce plastic waste.”
The Evolution of Survivorship After a Lung Cancer Diagnosis
“Key Takeaways: Survivorship evolved from enduring treatments to living a meaningful life, emphasizing daily love and giving back. Cancer altered Gillespie’s life perspective, sense of invincibility, and social interactions, leading to a more carefree outlook.”
‘Seesaw’ may explain why lung cancer treatments stop working
“A new discovery could help solve one of the most frustrating challenges in treating lung cancer: Why do some patients initially respond to drug treatment, only for it to stop working 18 months later?”
SRS Lessens Rate of Neurologic Death vs WBRT in SCLC and Brain Metastases
“Stereotactic radiation led to lower rates of neurologic death compared with whole-brain radiation (WBRT) in patients with small cell lung cancer (SCLC) and 1 to 10 brain metastases who were surveilled closely following treatment, according to results from a phase 2 trial (NCT03391362) published in the Journal of Clinical Oncology.”
Concomitant Use of Analgesics and EGFR TKIs in Lung Cancer Patients: Outcomes and Perspectives From a Finnish Retrospective Register-Based Study
“Introduction: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are used in the treatment of non-small cell lung cancer (NSCLC). Preclinical studies suggest inflammatory and other mechanisms of analgesics affect the efficacy of EGFR TKIs. In this study, we aim to explore the outcomes of concurrent use of EGFR TKIs and analgesics, to provide clinical insight into analgesic treatment decisions.”
