Duke researchers discover new origin of small cell lung cancer in study
“DURHAM, N.C. (WTVD) — Small cell lung cancer is one of the most aggressive and deadly forms of lung cancer commonly associated with smoking. Now, researchers at Duke Health have uncovered a surprising new origin of the disease. Inside the lab, Duke scientists developed advanced models to trace how tumor cells evolve and how they might be stopped before the cancer spreads.”
Common Medications Linked to Worse Survival in Lung Cancer Patients Receiving Keytruda
“Use of certain antibiotics, steroids and proton pump inhibitors (PPIs) at the start of immunotherapy was associated with shorter survival in patients with advanced non-small cell lung cancer (NSCLC), according to a nationwide cohort study from France published Sept. 10, 2025, in JAMA Network Open.”
A breath of hope: Cross-country journey will shine spotlight on lung cancer
“HIGH POINT — Dusty Donaldson will never forget the four words that changed her life two decades ago: “You have lung cancer.” The 71-year-old High Point woman remembers the shock. She remembers the fear. She remembers the depth of her ignorance about lung cancer and — once she began to learn — the sense of hopelessness that enveloped her. “At the time, I didn’t know lung cancer was the number-one cancer killer,” Donaldson says. “Like everyone else, I assumed it was breast cancer, but I was wrong. And I was shocked at the mortality rate for lung cancer — there was only a 15% survival rate at that time, so that’s an 85% mortality rate.” Twenty years later, though, Donaldson is cancer-free and is recognized as one of the nation’s most fiercely passionate advocates for lung cancer patients, dispensing knowledge, compassion and — perhaps most importantly — hope.”
Detection of ctDNA could help determine use of immunotherapy for small cell lung cancer
“Key takeaways: Patients with limited-stage small cell lung cancer with ctDNA positivity after chemotherapy had significant survival benefits from immunotherapy. Those who did not have detectable ctDNA did not.”
Motivation to Quit Smoking Highest Around the Time of Cancer Surgery
“Smoking before a cancer-related surgery is associated with a higher symptom burden, but the perioperative period is a prime time for patients to consider quitting, a JAMA Network Open study finds.”
World-renowned cancer doctor reveals his own diagnosis
“AURORA, Colo. (KDVR) – Dr. Ross Camidge is the director of the Thoracic Oncology Department at the University of Colorado Cancer Center. The doctor, who has an MD and Ph.D, has helped treat thousands of lung cancer patients from more than 40 states and over 40 countries. Now, in a life twist, Camidge is a lung cancer patient himself.”
Lung cancer screening guidance needed for certain never-smokers
“Key takeaways: Guidelines are needed for populations of never-smokers who have increased risk for lung cancer. Asian women who never smoked developed lung cancer at similar rates as groups with heightened risks.”
SHR-4849 Shows Activity With Manageable Safety in Relapsed Small Cell Lung Cancer
“The DLL3-directed antibody-drug conjugate (ADC) SHR-4849 (IDE849) demonstrated a tolerable toxicity profile and elicited responses in patients with relapsed small cell lung cancer (SCLC), according to preliminary data from a first-in-human phase 1 study (NCT06443489).”
Machine learning models can predict urgent care needs for patients with non–small cell lung cancer
“A new study published in JCO Clinical Cancer Informatics demonstrates that machine learning models incorporating patient-reported outcomes and wearable sensor data can predict which patients with non–small cell lung cancer are most at risk of needing urgent care during treatment.”
