Air Pollution ‘Strongly Associated’ With DNA Mutations Tied to Lung Cancer
“Lung cancer cases are on the rise in non-smokers around the world, and air pollution could be an insidious, contributing factor. A genome study has now found that outdoor smog and soot are strongly associated with DNA mutations related to lung cancer – including known drivers seen in smokers, and new ones unique to non-smokers.”
Recommendations for Interventions to Improve Function in Patients With Lung Cancer: A Clinical Practice Guideline
“Introduction: Individuals with lung cancer frequently experience functional limitations, yet best practice to achieve functional recovery has not been synthesized. This Clinical Practice Guideline generates evidence-based recommendations to improve functional outcomes in this population.”
The association between energy-adjusted dietary inflammatory index (E-DII) and lung cancer in 101,755 participants aged 55 years and above: a large prospective cohort
“Background: The association between the Dietary Inflammatory Index (DII) and lung cancer incidence remains unclear. This inconsistency may be attributed to not considering total energy intake and dietary supplement use adequately. To provide reliable evidence, we conducted a secondary analysis of data from the prospective Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial to examine the association between lung cancer incidence and E-DII (Energy-adjusted DII) derived from both food and supplements as well as from food only.”
With FDA Nod in Lung Cancer, Dizal Now Aims to Best a J&J Drug and Succeed Where Takeda Fell Short
“Dizal Pharmaceutical’s Zegfrovy is now FDA approved for treating non-small cell lung cancer driven by a particular rare genetic signature. Johnson & Johnson drug Rybrevant already addresses this genetic signature as an earlier line of therapy, but Dizal executives contend their drug offers the potential for better safety and efficacy.”
Don’t Wait for Symptoms: A Powerful Plea for Lung Cancer Screening from a Former Smoker
“No cough, no shortness of breath, no coughing up blood, and yet, a positive diagnosis for lung cancer. On November 28, 2024, Denise was preparing for her yearly Florida trip. She snuck in one last visit to her doctor to get her prescriptions filled before she left.”
Alzheimer’s protein found to drive lung cancer spread to the brain
“Researchers at McMaster University, Cleveland Clinic and Case Comprehensive Cancer Center have uncovered how a protein long associated with Alzheimer’s disease helps lung cancer spread to the brain – a discovery that offers hope that existing Alzheimer’s drugs could be repurposed in preventing cancer’s spread.”
‘Inoperable’ lung cancer to non-existent: The role genetic sequencing plays in treating tumors
“BURBANK, Calif. (KABC) — Cancer is not a welcome diagnosis, but breakthroughs in genetic sequencing and immunotherapy are making some cancers easier to treat than others. A local father and grandfather was told he had inoperable lung cancer, but six months later, it was in remission. The retired animator said it’s the kind of ending you might find in the world of Hollywood.”
Progress and challenges of artificial intelligence in lung cancer clinical translation
“Artificial intelligence (AI) algorithms, such as convolutional neural networks and transformers, have significantly impacted cancer care. For lung cancer, AI holds great potential in addressing smoking cessation, personalized screening, and imaging genomics. And these data could be incorporated to optimize treatment selection. This review highlights the transformative impact of AI in lung cancer management, discusses crucial barriers such as model bias and fairness, and outlines future directions for clinical application.”
Map Shows Worst US States for Lung Health
“Due to a combination of smoking rates, regional climates and air pollution, the health of Americans’ lungs varies immensely from state to state, according to a new report. A new study by Opera Beds, a specialist in clinically oriented mattresses and pressure-care systems, ranked the worst states for lung health in the U.S., drawing on data from the American Lung Association, the EPA and additional sources.”
