Invasive procedures rarely follow false-positive lung cancer screenings
“Key takeaways: Patients with false-positive lung cancer screening findings did not often undergo Invasive procedures. Procedure complications rarely occurred in patients without malignancy.”
Can your breath be used to detect lung cancer?
“In the first laboratory of its kind in North America, UBC’s Dr. Renelle Myers is harnessing the power of breath in the hopes of saving more lives, sooner.”
Nuvalent Initiates the Phase 2 Portion of ALKOVE-1 Clinical Trial for Patients with ALK-Positive NSCLC and other Solid Tumors
“CAMBRIDGE, Mass., Feb. 12, 2024 /PRNewswire/ — Nuvalent, Inc. (Nasdaq: NUVL), a clinical-stage biopharmaceutical company focused on creating precisely targeted therapies for clinically proven kinase targets in cancer, today announced the initiation of the Phase 2 portion of ALKOVE-1, its Phase 1/2 clinical trial of NVL-655 for patients with ALK-positive non-small cell lung cancer (NSCLC) and other solid tumors, following alignment with the US Food and Drug Administration (FDA) on a recommended Phase 2 dose (RP2D) of 150 mg once daily (QD).”
Enhancing Multidisciplinary Team Processes in Lung Cancer Care: A Self-Assessment Toolkit and Best Practices
“Multidisciplinary teams (MDTs) play a pivotal role in the comprehensive management of cancer. MDT meetings (MDTMs) bring together specialized experts across the entire patient care spectrum, convening regularly to discuss patient cases, select optimal diagnostic strategies, and determine the most appropriate treatment modalities. By fostering cross-disciplinary interaction, MDTs aim to enhance patient outcomes and elevate the collective proficiency within a health care institution, promoting knowledge dissemination and ensuring health care practitioners remain abreast of the latest clinical insights.”
As cancer treatment advances, patients and doctors push back against drugs’ harsh side effects
“For cancer patients, the harsh side effects of powerful drugs have long been the trade-off for living longer. Now, patients and doctors are questioning whether all that suffering is necessary.”
Worth The Wait? Genomic Testing Delays Initiation of Advanced NSCLC Therapy
“Participants in virtual events discussed the key issue of whether to initiate therapy immediately or wait for test results that could show the best approach in patients with advanced lung cancer.”
How One Type of Lung Cancer Can Transform into Another
“Lung tumors called adenocarcinomas sometimes respond to initially effective treatments by transforming into a much more aggressive small cell lung cancer (SCLC) that spreads rapidly and has few options for treatment. Researchers at Weill Cornell Medicine have developed a mouse model that illuminates this problematic process, known as histological transformation. The findings advance the understanding of how mutated genes can trigger cancer evolution and suggest targets for more effective treatments.”
New immunotherapy borrows cancer’s tricks to unleash powerful T cells
“Immunotherapies using engineered T cells have ushered in a new era in cancer treatment, but they have their limits. They may cause side effects or stop working, and they do not work at all against 90% of cancers. Now, scientists at UC San Francisco and Northwestern Medicine may have found a way around these limitations by borrowing a few tricks from cancer itself.”
Bristol Myers’ (BMY) Opdivo Label Expansion Filings Get Accepted
“Bristol Myers BMY announced the acceptance of its regulatory applications for neoadjuvant Opdivo (nivolumab) with chemotherapy followed by surgery and adjuvant Opdivo for the perioperative treatment of resectable stage IIA to IIIB non-small cell lung cancer (NSCLC) in the United States and EU.”
Quitting smoking greatly reduces the risk of deadly cancers
“In a study that underscores the vast health benefits of quitting smoking, researchers have found compelling evidence that kicking the habit can significantly decrease the risk of developing cancer. The study revealed that the benefits of quitting smoking accumulate over time and are particularly pronounced after the first decade of cessation.”
Video:
3 Decades, 3 Cancers: Stacey Sager’s story of perseverance, sacrifice and survival
“For anyone who has ever faced a cancer diagnosis, Eyewitness News Reporter Stacey Sager describes the importance of speaking up, never giving up, and knowing your own body.”
Clinicians Face Off Regarding New Trials in NSCLC Space
“In a recent Face-Off program hosted by CancerNetwork, experts went head-to-head to discuss recent data on non–small cell lung cancer (NSCLC). The panelists were split into 2 teams, the Jets and the Giants, and presented data regarding recent advancements and pivotal trial results in the field.”