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Comparing Small Cell and Non-Small Cell Lung Cancer
“Lung cancer is the second most common cancer in the country, accounting for about 1 in every 5 cancer related deaths, according to the American Cancer Society. While “lung cancer” is an umbrella term, the malignancy can be looked at as separate diseases with non-small cell lung cancer being the most common.”

Transforming Lung Cancer Resection: Evolution of Quality through Lymph Node Kit Implementation
“The following is a summary of “Institution-Level Evolution of Lung Cancer Resection Quality With Implementation of a Lymph Node Specimen Collection Kit,” published in the July 2023 issue of the Thoracic Oncology by Akinbobola et al.”

Tarlatamab induces response in relapsed small cell lung cancer
“Tarlatamab exhibited activity among patients with relapsed or refractory small cell lung cancer, according to the agent’s manufacturer.”

Genetic Profiles Affect Smokers’ Lung Cancer Risk
”MADRID — Smokers with extreme phenotypes of high and low risk of developing tobacco-associated lung cancer have different genetic profiles, according to a multidisciplinary study conducted by specialists from the Cancer Center at the University of Navarra Clinic (CUN). The results were presented at the last meeting of the American Society for Clinical Oncology held in Chicago, United States.”

Lilly’s Retevmo Beats PD-1 Combo for RET Fusion-Positive Lung Cancer
“Topline results from the late-stage LIBRETTO-431 study evaluating the efficacy of Eli Lilly’s oral targeted cancer therapy Retevmo (selpercatinib) in participants with advanced or metastatic rearranged during transfection (RET) fusion-positive non-small cell lung cancer (NSCLC), show increased progression free survival compared to treatment with a PD-1 inhibitor plus chemotherapy.”

Phase 3 Study of Selpercatinib Meets Primary PFS End Point in NSCLC
“Selpercatinib (Retevmo) given as an initial treatment for patients with RET fusion-positive advanced or metastatic non–small cell lung cancer (NSCLC) demonstrated a statistically significant and clinically meaningful improvement in progression-free survival (PFS) vs platinum-based chemotherapy plus pemetrexed with or without pembrolizumab (Keytruda), meeting the primary end point of the LIBRETTO-431 study (NCT04194944).”

Scientists say they can short-circuit lung cancer gene
“In tests on mice, they were able to block the switch that drives abnormal cell growth, so that tumors shrank permanently.”

Fine Particulate Matter Exposure May Increase Risk of Primary Cancers Other Than Lung Cancer
“Chronic exposure to fine particulate air pollutants (PM2.5, particulate matter 2.5 µm in diameter) and nitrogen dioxide (NO2) may increase non-lung cancer risk in older adults, according to a study published by Yaguang et al in Environmental Epidemiology. In a cohort study of millions of Medicare bneficiaries, researchers found that exposures to PM2.5 and NO2 over a 10-year period increased the risk of developing colorectal and prostate cancers. They also found that even low levels of air pollution exposure may make individuals particularly susceptible to developing these cancers, in addition to breast and endometrial cancers.”

Ask the Doctors: Radon gas in homes can lead to lung cancer
“Q: Would you please address radon gas? I’ve spent 40 years in real estate sales here in Florida, and while radon is noted in inspections, most buyers don’t realize it’s dangerous. Any information about the health risks, and how to protect yourself, could help a lot of people.”